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Synthetic biodegradable polymers

iciples; Coordination geometries of schiff -base metal complexes; Recent studies of (Salen) MX-Catalyzed copolymerization processes; Summary

Thông tin trích dẫn: Synthetic biodegradable polymers. Bernhard Rieger#Andears Kunkel#Geaffrey Reichardt#Eckhard Ninius#Thomas A.Zevaco. NXB Springer, 2012.

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Synthetic biodegradable polymers are widely used in medicine and biology and are essential components of drug delivery vehicles, tissue engineering scaffolds, and biomedical devices. There is, therefore, great interest in designing new synthetic biodegradable polymers for biomedical applications. A key property that controls the function and effectiveness of biomedical polymers is their rate of degradation. In this review article, we will describe the physical and chemical mechanisms by which the major classes of biomedical polymers degrade. In particular, the hydrolysis of polyesters, polyanhydrides, polyorthoesters, and polyketals is discussed. The hydrolysis of these polymers by water is described, and the factors that influence their water hydrolysis rates are also discussed, such as catalysis of hydrolysis by acid, base, and enzymes. In addition, the physical factors that influence polymer hydrolysis rates will also be described, such as polymer crystallinity and hydrophobicity. We anticipate that this information will provide the basis for predicting the hydrolysis kinetics of synthetic polymers and will assist in the design of new polymers for biomedical applications.

Từ khóa: Synthetic;biodegradable;polymers, Công nghệ Hóa, Môi trường, Bernhard Rieger#Andears Kunkel#Geaffrey Reichardt#Eckhard Ninius#Thomas A.Zevaco

11 p tailieu_haui 21/06/2022 48 0

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